Rhythm-DNB
How changes in physiological and behavioural signals can help identify transitions in biological rhythms.
A
B
C
D
- Spread of A, B, C
- 1.14
- Correlation within
- 0.16
- Correlation with D
- 0.05
Index3.3
Close to a tipping point a system recovers slowly from small disturbances. A group of its signals starts to swing more and to swing together, while staying unrelated to the rest. The index multiplies the group’s spread by its inner correlation and divides by its correlation with everything else, so it rises only when all three change at once.
Approach
- Longitudinal physiological and behavioural records
- Population DNB and individual sDNB, computed separately
- Controlled simulations with known transitions
- Comparison with independent rhythm measures
- Counter-examples kept beside the successes
My part
I study Dynamical Network Biomarkers (DNB) and their individual-level form, sDNB, through longitudinal analysis and controlled simulations, with particular attention to when these methods can be relied on.
Limits
- A rising index is a warning sign, not a diagnosis: whether it comes early enough, and for whom, is the open question.